Consumer genetics pioneer dnaNUDGE – Finalist of World Technology Award for Health & Medicine – Becomes Member of WTN

London, UK, 24th January 2017 – dnaNUDGE, the developer of the world’s first DNA-based service to “nudge” consumers towards genetically optimal buying behaviour, today announces that it has become a member of the prestigious World Technology Network (WTN), acceding automatically as a finalist in the World Technology Award for Health and Medicine 2016.

For more information read the full news release here:

Research sheds light into genetic mechanisms driving breast cancer progression

Researchers at UT Southwestern Medical Center have uncovered how the body's inflammatory response can alter how estrogen promotes the growth of breast cancer cells. Researchers identified how a combination of signaling molecules inhibits the growth of breast cancer cells, improving clinical outcomes for some subtypes of breast cancers.

The combination -- the steroid hormone estradiol and the proinflammatory cytokine tumor necrosis factor alpha (TNFα) -- act to expand the number of sites where estrogen receptor alpha (ERα) can bind to the genome in breast cancer cells. The new sites of ERα binding turn new genes on and off, which alters the growth response of the breast cancer cells, inhibiting their growth and improving clinical outcomes in certain cases.

The newly identified gene set can be used as a biomarker that can help physicians determine who is at risk and how they might react to certain therapies.


Obese children taken off at-risk register after genes found to be at fault

Two children considered to be at risk of abuse because they are severely obese have been removed from the protection register after scientists discovered that they carry a newly identified genetic abnormality that explains their weight.

Evidence from a ground-breaking study has convinced social workers that the children’s obesity was not caused by parental neglect or deliberate overfeeding but by a missing segment of DNA. The cases of another two children on the at-risk register have also been placed under review, after research showed them to have the same genetic deletion.



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